Add aerosolized virus factor into the exposure model
Following the meeting with Dr. Julian Tang (06/07/2021), he points to evidence that the viral load (density of viruses) from NP swabs is NOT conserved when the respiratory fluid is exhaled in the form of aerosols. I.e. imagine that:
viral load = 10^6 copies / mL;
Volumetric aerosol emission rate = 1 mL / h;
Viral emission rate is NOT = 10^6 copies / h ... it is less than that
A reduction factor is needed. A couple of papers show a 10^2 - 10^4 reduction in the ration between copies from NP swabs and copies in aerosol samples.
Data: https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1003205
https://www.pnas.org/content/115/5/1081
https://pubmed.ncbi.nlm.nih.gov/25083787/
Data in excel file: NP_vs_aerosol_RNA_copies.xlsx