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Avoid using time-dependence of parameters in concentration computation

In ConcentrationModel, the parameters (which are assumed to be constant for the formula to be valid) are computed only at the next state change.

Also providing the new methods (non public) _next_state_change and _concentration_limit - the latter improves code readability and will be useful for the integration of the concentration with an analytic formula.

Solves #161 (closed)

Edited by Nicolas Mounet

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